Aberrant DNA methylation reprogramming during induced pluripotent stem cell generation is dependent on the choice of reprogramming factors

The conversion of somatic cells into pluripotent stem cells via overexpression of reprogramming factors involves epigenetic remodeling. DNA methylation at a significant proportion of CpG sites in induced pluripotent stem cells (iPSCs) differs from that of embryonic stem cells (ESCs). Whether differe...

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Detalles Bibliográficos
Autores principales: Planello, Aline C, Ji, Junfeng, Sharma, Vivek, Singhania, Rajat, Mbabaali, Faridah, Müller, Fabian, Alfaro, Javier A, Bock, Christoph, De Carvalho, Daniel D, Batada, Nizar N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230737/
https://www.ncbi.nlm.nih.gov/pubmed/25408883
http://dx.doi.org/10.1186/2045-9769-3-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230737/
https://www.ncbi.nlm.nih.gov/pubmed/25408883
http://dx.doi.org/10.1186/2045-9769-3-4

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