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The Red Queen Model of Recombination Hotspots Evolution in the Light of Archaic and Modern Human Genomes

Recombination is an essential process in eukaryotes, which increases diversity by disrupting genetic linkage between loci and ensures the proper segregation of chromosomes during meiosis. In the human genome, recombination events are clustered in hotspots, whose location is determined by the PRDM9 p...

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Detalles Bibliográficos
Autores principales: Lesecque, Yann, Glémin, Sylvain, Lartillot, Nicolas, Mouchiroud, Dominique, Duret, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230742/
https://www.ncbi.nlm.nih.gov/pubmed/25393762
http://dx.doi.org/10.1371/journal.pgen.1004790