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The Red Queen Model of Recombination Hotspots Evolution in the Light of Archaic and Modern Human Genomes
Recombination is an essential process in eukaryotes, which increases diversity by disrupting genetic linkage between loci and ensures the proper segregation of chromosomes during meiosis. In the human genome, recombination events are clustered in hotspots, whose location is determined by the PRDM9 p...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230742/ https://www.ncbi.nlm.nih.gov/pubmed/25393762 http://dx.doi.org/10.1371/journal.pgen.1004790 |