Targeted genome engineering in human induced pluripotent stem cells by penetrating TALENs

BACKGROUND: Zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs) have been successfully used to knock out endogenous genes in stem cell research. However, the deficiencies of current gene-based delivery systems may hamper the clinical application of these nucleas...

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Detalles Bibliográficos
Autores principales: Ru, Renli, Yao, Yongchao, Yu, Songlin, Yin, Benpeng, Xu, Wanwan, Zhao, Siting, Qin, Li, Chen, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230761/
https://www.ncbi.nlm.nih.gov/pubmed/25408877
http://dx.doi.org/10.1186/2045-9769-2-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230761/
https://www.ncbi.nlm.nih.gov/pubmed/25408877
http://dx.doi.org/10.1186/2045-9769-2-5

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