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A(1) adenosine receptor–stimulated exocytosis in bladder umbrella cells requires phosphorylation of ADAM17 Ser-811 and EGF receptor transactivation

Despite the importance of ADAM17-dependent cleavage in normal biology and disease, the physiological cues that trigger its activity, the effector pathways that promote its function, and the mechanisms that control its activity, particularly the role of phosphorylation, remain unresolved. Using nativ...

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Detalles Bibliográficos
Autores principales: Prakasam, H. Sandeep, Gallo, Luciana I., Li, Hui, Ruiz, Wily G., Hallows, Kenneth R., Apodaca, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230785/
https://www.ncbi.nlm.nih.gov/pubmed/25232008
http://dx.doi.org/10.1091/mbc.E14-03-0818