Cargando…

p53- and ERK7-Dependent Ribosome Surveillance Response Regulates Drosophila Insulin-Like Peptide Secretion

Insulin-like signalling is a conserved mechanism that coordinates animal growth and metabolism with nutrient status. In Drosophila, insulin-producing median neurosecretory cells (IPCs) regulate larval growth by secreting insulin-like peptides (dILPs) in a diet-dependent manner. Previous studies have...

Descripción completa

Detalles Bibliográficos
Autores principales: Hasygar, Kiran, Hietakangas, Ville
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230838/
https://www.ncbi.nlm.nih.gov/pubmed/25393288
http://dx.doi.org/10.1371/journal.pgen.1004764