Vortioxetine disinhibits pyramidal cell function and enhances synaptic plasticity in the rat hippocampus

Vortioxetine, a novel antidepressant with multimodal action, is a serotonin (5-HT)(3), 5-HT(7) and 5-HT(1D) receptor antagonist, a 5-HT(1B) receptor partial agonist, a 5-HT(1A) receptor agonist and a 5-HT transporter (SERT) inhibitor. Vortioxetine has been shown to improve cognitive performance in s...

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Detalles Bibliográficos
Autores principales: Dale, Elena, Zhang, Hong, Leiser, Steven C, Xiao, Yixin, Lu, Dunguo, Yang, Charles R, Plath, Niels, Sanchez, Connie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2014
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230848/
https://www.ncbi.nlm.nih.gov/pubmed/25122043
http://dx.doi.org/10.1177/0269881114543719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230848/
https://www.ncbi.nlm.nih.gov/pubmed/25122043
http://dx.doi.org/10.1177/0269881114543719

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