Potentiation of latent inhibition by haloperidol and clozapine is attenuated in Dopamine D2 receptor (Drd-2)-deficient mice: Do antipsychotics influence learning to ignore irrelevant stimuli via both Drd-2 and non-Drd-2 mechanisms?

Whether the dopamine Drd-2 receptor is necessary for the behavioural action of antipsychotic drugs is an important question, as Drd-2 antagonism is responsible for their debilitating motor side effects. Using Drd-2 null mice (Drd(2) -/-) it has previously been shown that Drd-2 is not necessary for a...

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Detalles Bibliográficos
Autores principales: O’Callaghan, Matthew J, Bay-Richter, Cecilie, O’Tuathaigh, Colm MP, Heery, David M, Waddington, John L, Moran, Paula M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2014
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230883/
https://www.ncbi.nlm.nih.gov/pubmed/25122042
http://dx.doi.org/10.1177/0269881114544774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230883/
https://www.ncbi.nlm.nih.gov/pubmed/25122042
http://dx.doi.org/10.1177/0269881114544774

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