TLR9 Activation Is Triggered by the Excess of Stimulatory versus Inhibitory Motifs Present in Trypanosomatidae DNA

DNA sequences purified from distinct organisms, e.g. non vertebrate versus vertebrate ones, were shown to differ in their TLR9 signalling properties especially when either mouse bone marrow-derived- or human dendritic cells (DCs) are probed as target cells. Here we found that the DC-targeting immuno...

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Detalles Bibliográficos
Autores principales: Khan, Mélissa Erin, Borde, Chloé, Rocha, Eduardo P.C., Mériaux, Véronique, Maréchal, Vincent, Escoll, Pedro, Goyard, Sophie, Cavaillon, Jean-Marc, Manoury, Bénédicte, Doyen, Noëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230925/
https://www.ncbi.nlm.nih.gov/pubmed/25392997
http://dx.doi.org/10.1371/journal.pntd.0003308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230925/
https://www.ncbi.nlm.nih.gov/pubmed/25392997
http://dx.doi.org/10.1371/journal.pntd.0003308

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