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Plasmodium falciparum Transfected with Ultra Bright NanoLuc Luciferase Offers High Sensitivity Detection for the Screening of Growth and Cellular Trafficking Inhibitors

Drug discovery is a key part of malaria control and eradication strategies, and could benefit from sensitive and affordable assays to quantify parasite growth and to help identify the targets of potential anti-malarial compounds. Bioluminescence, achieved through expression of exogenous luciferases,...

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Detalles Bibliográficos
Autores principales: Azevedo, Mauro F., Nie, Catherine Q., Elsworth, Brendan, Charnaud, Sarah C., Sanders, Paul R., Crabb, Brendan S., Gilson, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231029/
https://www.ncbi.nlm.nih.gov/pubmed/25392998
http://dx.doi.org/10.1371/journal.pone.0112571