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Proteome Folding Kinetics Is Limited by Protein Halflife
How heterogeneous are proteome folding timescales and what physical principles, if any, dictate its limits? We answer this by predicting copy number weighted folding speed distribution – using the native topology – for E.coli and Yeast proteome. E.coli and Yeast proteomes yield very similar distribu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231061/ https://www.ncbi.nlm.nih.gov/pubmed/25393560 http://dx.doi.org/10.1371/journal.pone.0112701 |