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Proteome Folding Kinetics Is Limited by Protein Halflife

How heterogeneous are proteome folding timescales and what physical principles, if any, dictate its limits? We answer this by predicting copy number weighted folding speed distribution – using the native topology – for E.coli and Yeast proteome. E.coli and Yeast proteomes yield very similar distribu...

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Detalles Bibliográficos
Autores principales: Zou, Taisong, Williams, Nickolas, Ozkan, S. Banu, Ghosh, Kingshuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231061/
https://www.ncbi.nlm.nih.gov/pubmed/25393560
http://dx.doi.org/10.1371/journal.pone.0112701

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