Ca(2+)-Induced PRE-NMR Changes in the Troponin Complex Reveal the Possessive Nature of the Cardiac Isoform for Its Regulatory Switch

The interaction between myosin and actin in cardiac muscle, modulated by the calcium (Ca(2+)) sensor Troponin complex (Tn), is a complex process which is yet to be fully resolved at the molecular level. Our understanding of how the binding of Ca(2+) triggers conformational changes within Tn that are...

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Detalles Bibliográficos
Autores principales: Cordina, Nicole M., Liew, Chu K., Potluri, Phani R., Curmi, Paul M., Fajer, Piotr G., Logan, Timothy M., Mackay, Joel P., Brown, Louise J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231091/
https://www.ncbi.nlm.nih.gov/pubmed/25392916
http://dx.doi.org/10.1371/journal.pone.0112976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231091/
https://www.ncbi.nlm.nih.gov/pubmed/25392916
http://dx.doi.org/10.1371/journal.pone.0112976

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