Possible Contribution of Taurine to Distorted Glucagon Secretion in Intra-Islet Insulin Deficiency: A Metabolome Analysis Using a Novel α-Cell Model of Insulin-Deficient Diabetes

Glycemic instability is a serious problem in patients with insulin-deficient diabetes, and it may be due in part to abnormal endogenous glucagon secretion. However, the intracellular metabolic mechanism(s) involved in the aberrant glucagon response under the condition of insulin deficiency has not y...

Descripción completa

Detalles Bibliográficos
Autores principales: Bessho, Megumi, Murase-Mishiba, Yuko, Imagawa, Akihisa, Terasaki, Jungo, Hanafusa, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231115/
https://www.ncbi.nlm.nih.gov/pubmed/25393115
http://dx.doi.org/10.1371/journal.pone.0113254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231115/
https://www.ncbi.nlm.nih.gov/pubmed/25393115
http://dx.doi.org/10.1371/journal.pone.0113254

Ejemplares similares