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The E3 ubiquitin ligase TRIM62 and inflammation-induced skeletal muscle atrophy
INTRODUCTION: ICU-acquired weakness (ICUAW) complicates the disease course of critically ill patients. Inflammation and acute-phase response occur directly within myocytes and contribute to ICUAW. We observed that tripartite motif–containing 62 (TRIM62), an E3 ubiquitin ligase and modifier of inflam...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231194/ https://www.ncbi.nlm.nih.gov/pubmed/25263070 http://dx.doi.org/10.1186/s13054-014-0545-6 |