A unique DNA methylation signature defines a population of IFN-γ/IL-4 double-positive T cells during helminth infection

Th1 and Th2 cell fates are traditionally viewed as mutually exclusive, but recent work suggests that these lineages may be more plastic than previously thought. When isolating splenic CD4(+) T cells from mice infected with the parasitic helminth Schistosoma mansoni, we observed a defined population...

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Detalles Bibliográficos
Autores principales: Deaton, Aimée M, Cook, Peter C, De Sousa, Dina, Phythian-Adams, Alexander T, Bird, Adrian, MacDonald, Andrew S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag GmbH & Co 2014
Materias:
Molecular Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231227/
https://www.ncbi.nlm.nih.gov/pubmed/24578067
http://dx.doi.org/10.1002/eji.201344098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231227/
https://www.ncbi.nlm.nih.gov/pubmed/24578067
http://dx.doi.org/10.1002/eji.201344098

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