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A unique DNA methylation signature defines a population of IFN-γ/IL-4 double-positive T cells during helminth infection
Th1 and Th2 cell fates are traditionally viewed as mutually exclusive, but recent work suggests that these lineages may be more plastic than previously thought. When isolating splenic CD4(+) T cells from mice infected with the parasitic helminth Schistosoma mansoni, we observed a defined population...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag GmbH & Co
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231227/ https://www.ncbi.nlm.nih.gov/pubmed/24578067 http://dx.doi.org/10.1002/eji.201344098 |