Independent oncogenic and therapeutic significance of phosphatase PRL-3 in FLT3-ITD–negative acute myeloid leukemia

BACKGROUND: Internal tandem duplication of FMS-like tyrosine kinase (FLT3-ITD) is well known to be involved in acute myeloid leukemia (AML) progression, but FLT3-ITD–negative AML cases account for 70% to 80% of AML, and the mechanisms underlying their pathology remain unclear. This study identifies...

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Detalles Bibliográficos
Autores principales: Qu, Shuang, Liu, Bin, Guo, Xiaoling, Shi, Hongshun, Zhou, Meifeng, Li, Li, Yang, Shulan, Tong, Xiuzhen, Wang, Haihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231236/
https://www.ncbi.nlm.nih.gov/pubmed/24737397
http://dx.doi.org/10.1002/cncr.28668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231236/
https://www.ncbi.nlm.nih.gov/pubmed/24737397
http://dx.doi.org/10.1002/cncr.28668

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