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Paraneoplastic CDR2 and CDR2L antibodies affect Purkinje cell calcium homeostasis

Paraneoplastic cerebellar degeneration (PCD) is characterized by loss of Purkinje cells (PCs) associated with progressive pancerebellar dysfunction in the presence of onconeural Yo antibodies. These antibodies recognize the cerebellar degeneration-related antigens CDR2 and CDR2L. Response to PCD the...

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Detalles Bibliográficos
Autores principales: Schubert, Manja, Panja, Debabrata, Haugen, Mette, Bramham, Clive R., Vedeler, Christian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231287/
https://www.ncbi.nlm.nih.gov/pubmed/25341622
http://dx.doi.org/10.1007/s00401-014-1351-6