P2Y(6) receptor inhibition perturbs CCL2-evoked signalling in human monocytic and peripheral blood mononuclear cells

The chemokine CCL2 serves to target circulating monocytes and other leukocytes to tissue during innate immune responses, and modulates the progression of chronic inflammatory disease through activation of the receptor CCR2. Here, we show that co-activation of the P2Y(6) purinergic receptor (encoded...

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Detalles Bibliográficos
Autores principales: Campwala, Hinnah, Sexton, Darren W., Crossman, David C., Fountain, Samuel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231309/
https://www.ncbi.nlm.nih.gov/pubmed/25271060
http://dx.doi.org/10.1242/jcs.159012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231309/
https://www.ncbi.nlm.nih.gov/pubmed/25271060
http://dx.doi.org/10.1242/jcs.159012

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