Cargando…

Effects of Tet-mediated Oxidation Products of 5-Methylcytosine on DNA Transcription in vitro and in Mammalian Cells

5-methylcytosine (5-mC) is a well-characterized epigenetic regulator in mammals. Recent studies showed that Ten-eleven translocation (Tet) proteins can catalyze the stepwise oxidation of 5-mC to produce 5-hydroxymethylcytosine (5-HmC), 5-formylcytosine (5-FoC) and 5-carboxylcytosine (5-CaC). The exc...

Descripción completa

Detalles Bibliográficos
Autores principales:	You, Changjun, Ji, Debin, Dai, Xiaoxia, Wang, Yinsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231326/ https://www.ncbi.nlm.nih.gov/pubmed/25394478 http://dx.doi.org/10.1038/srep07052

Ejemplares similares

Effects of Tet-Induced Oxidation Products of 5-Methylcytosine on DNA Replication in Mammalian Cells
por: Ji, Debin, et al.
Publicado: (2014)

Quantitative assessment of Tet-induced oxidation products of 5-methylcytosine in cellular and tissue DNA
por: Liu, Shuo, et al.
Publicado: (2013)

TET-mediated 5-methylcytosine oxidation in tRNA promotes translation
por: Shen, Hui, et al.
Publicado: (2020)

Epigenetic TET-Catalyzed Oxidative Products of 5-Methylcytosine Impede Z-DNA Formation of CG Decamers
por: Vongsutilers, Vorasit, et al.
Publicado: (2020)

TET-mediated oxidation of methylcytosine causes TDG or NEIL glycosylase dependent gene reactivation
por: Müller, Udo, et al.
Publicado: (2014)

Genome-wide analysis reveals TET-and TDG-mediated 5-methylcytosine oxidation dynamics
por: Shen, Li, et al.
Publicado: (2013)

Genome-wide analysis reveals TET-and TDG-mediated 5-methylcytosine oxidation dynamics
por: Shen, Li, et al.
Publicado: (2013)

Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA
por: Hashimoto, Hideharu, et al.
Publicado: (2013)

Transcriptional inhibition and mutagenesis induced by N-nitroso compound-derived carboxymethylated thymidine adducts in DNA
por: You, Changjun, et al.
Publicado: (2015)

TET‐Like Oxidation in 5‐Methylcytosine and Derivatives: A Computational and Experimental Study
por: Jonasson, Niko S. W., et al.
Publicado: (2021)

Tet2 Catalyzes Stepwise 5-Methylcytosine Oxidation by an Iterative and de novo Mechanism
por: Crawford, Daniel J., et al.
Publicado: (2016)

Accurate estimation of 5-methylcytosine in mammalian mitochondrial DNA
por: Matsuda, Shigeru, et al.
Publicado: (2018)

Enhanced 5-methylcytosine detection in single-molecule, real-time sequencing via Tet1 oxidation
por: Clark, Tyson A, et al.
Publicado: (2013)

TET Methylcytosine Oxidases in T Cell and B Cell Development and Function
por: Tsagaratou, Ageliki, et al.
Publicado: (2017)

Isoform-specific and ubiquitination dependent recruitment of Tet1 to replicating heterochromatin modulates methylcytosine oxidation
por: Arroyo, María, et al.
Publicado: (2022)

Transcriptional bypass of regioisomeric ethylated thymidine lesions by T7 RNA polymerase and human RNA polymerase II
por: You, Changjun, et al.
Publicado: (2014)

Tet-Mediated Formation of 5-Hydroxymethylcytosine in RNA
por: Fu, Lijuan, et al.
Publicado: (2014)

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
por: Ko, Myunggon, et al.
Publicado: (2010)

Mutagenic and Cytotoxic Properties of Oxidation Products of 5-Methylcytosine Revealed by Next-Generation Sequencing
por: Xing, Xi-Wen, et al.
Publicado: (2013)

Characterizing 5-methylcytosine in the mammalian epitranscriptome
por: Hussain, Shobbir, et al.
Publicado: (2013)

A Quantitative Assay for Assessing the Effects of DNA Lesions on Transcription
por: You, Changjun, et al.
Publicado: (2012)

Optochemical Control of TET Dioxygenases Enables Kinetic Insights into the Domain-Dependent Interplay of TET1 and MBD1 while Oxidizing and Reading 5-Methylcytosine
por: Lin, Tzu-Chen, et al.
Publicado: (2022)

Author Correction: Isoform-specific and ubiquitination dependent recruitment of Tet1 to replicating heterochromatin modulates methylcytosine oxidation
por: Arroyo, María, et al.
Publicado: (2023)

Deamination of 5-Methylcytosine Residues in Mammalian Cells
por: Gromenko, E.V., et al.
Publicado: (2009)

Base-resolution detection of N(4)-methylcytosine in genomic DNA using 4mC-Tet-assisted-bisulfite- sequencing
por: Yu, Miao, et al.
Publicado: (2015)

Flanking sequences influence the activity of TET1 and TET2 methylcytosine dioxygenases and affect genomic 5hmC patterns
por: Adam, Sabrina, et al.
Publicado: (2022)

A TET Homologue Protein from Coprinopsis cinerea (CcTET) That Biochemically Converts 5-Methylcytosine to 5-Hydroxymethylcytosine, 5-Formylcytosine, and 5-Carboxylcytosine
por: Zhang, Liang, et al.
Publicado: (2014)

Position-dependent effects of regioisomeric methylated adenine and guanine ribonucleosides on translation
por: You, Changjun, et al.
Publicado: (2017)

Dual functions of TET1 in germ layer lineage bifurcation distinguished by genomic context and dependence on 5-methylcytosine oxidation
por: van der Veer, Bernard K, et al.
Publicado: (2023)

Hyperglycemia affects global 5-methylcytosine and 5-hydroxymethylcytosine in blood genomic DNA through upregulation of SIRT6 and TETs
por: Yuan, Er-Feng, et al.
Publicado: (2019)

Formation and determination of the oxidation products of 5-methylcytosine in RNA
por: Huang, Wei, et al.
Publicado: (2016)

Optimized bisulfite sequencing analysis reveals the lack of 5-methylcytosine in mammalian mitochondrial DNA
por: Shao, Zhenyu, et al.
Publicado: (2023)

Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells
por: Putiri, Emily L, et al.
Publicado: (2014)

Tet methylcytosine dioxygenase 2 inhibits atherosclerosis via upregulation of autophagy in ApoE(−/−) mice
por: Peng, Juan, et al.
Publicado: (2016)

Molecular mechanism for vitamin C-derived C(5)-glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1
por: Li, Wenjing, et al.
Publicado: (2021)

Facile Enzymatic Synthesis of Base J-Containing Oligodeoxyribonucleotides and an Analysis of the Impact of Base J on DNA Replication in Cells
por: Ji, Debin, et al.
Publicado: (2014)

Hydroxyl-radical-induced oxidation of 5-methylcytosine in isolated and cellular DNA
por: Madugundu, Guru S., et al.
Publicado: (2014)

TET2 Mutations Are Associated with Specific 5-Methylcytosine and 5-Hydroxymethylcytosine Profiles in Patients with Chronic Myelomonocytic Leukemia
por: Pérez, Cristina, et al.
Publicado: (2012)

Tet1 facilitates hypoxia tolerance by stabilizing the HIF-α proteins independent of its methylcytosine dioxygenase activity
por: Wang, Jing, et al.
Publicado: (2017)

NSUN2 introduces 5-methylcytosines in mammalian mitochondrial tRNAs
por: Van Haute, Lindsey, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_mh8bm19oov9qp3dkpeaanb00dg