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Functional and differential proteomic analyses to identify platelet derived factors affecting ex vivo expansion of mesenchymal stromal cells

BACKGROUND: Multilineage differentiation, immunomodulation and secretion of trophic factors render mesenchymal stromal cells (MSC) highly attractive for clinical application. Human platelet derivatives such as pooled human platelet lysate (pHPL) and thrombin-activated platelet releasate in plasma (t...

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Detalles Bibliográficos
Autores principales: Kinzebach, Sven, Dietz, Lisa, Klüter, Harald, Thierse, Hermann-Josef, Bieback, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231358/
https://www.ncbi.nlm.nih.gov/pubmed/24168020
http://dx.doi.org/10.1186/1471-2121-14-48