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Certain Diet and Lifestyle May Contribute to Islet β-cells Protection in Type-2 Diabetes via the Modulation of Cellular PI3K/AKT Pathway

PI3K/AKT pathway has been shown to play a pivotal role on islet β-cell protection, enhancing β-cell survival by stimulating cell proliferation and inhibiting cell apoptosis. Accordingly, this pathway appears to be crucial in type-2 diabetes. Understanding the regulations of this pathway may provide...

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Detalles Bibliográficos
Autores principales: Kitagishi, Yasuko, Nakanishi, Atsuko, Minami, Akari, Asai, Yurina, Yasui, Mai, Iwaizako, Akiko, Suzuki, Miho, Ono, Yuna, Ogura, Yasunori, Matsuda, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231374/
https://www.ncbi.nlm.nih.gov/pubmed/25400709
http://dx.doi.org/10.2174/1874091X01408010074