In-silico docking based design and synthesis of [1H,3H] imidazo[4,5-b] pyridines as lumazine synthase inhibitors for their effective antimicrobial activity

PURPOSE: The imidazopyridine moiety is important pharmacophore that has proven to be useful for a number of biologically relevant targets, also reported to display antibacterial, antifungal, antiviral properties. Riboflavin biosynthesis involving catalytic step of Lumazine synthase is absent in anim...

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Detalles Bibliográficos
Autores principales: Harer, Sunil L., Bhatia, Manish S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231389/
https://www.ncbi.nlm.nih.gov/pubmed/25400412
http://dx.doi.org/10.4103/0975-7406.142962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231389/
https://www.ncbi.nlm.nih.gov/pubmed/25400412
http://dx.doi.org/10.4103/0975-7406.142962

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