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Effect of methotrexate conjugated PAMAM dendrimers on the viability of MES-SA uterine cancer cells

The aim of this work was to synthesize methotrexate (MTX)-polyamidoamine (PAMAM) dendritic nanoconjugates and to study their effect on cell viability in uterine sarcoma cells. The amide-bonded PAMAM dendrimer-MTX conjugates were prepared by conjugation between the amine-terminated G5 dendrimer and t...

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Detalles Bibliográficos
Autores principales: Khatri, Samreen, Das, Nandita G., Das, Sudip K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231390/
https://www.ncbi.nlm.nih.gov/pubmed/25400413
http://dx.doi.org/10.4103/0975-7406.142963