Reconstruction of large-scale regulatory networks based on perturbation graphs and transitive reduction: improved methods and their evaluation

BACKGROUND: The data-driven inference of intracellular networks is one of the key challenges of computational and systems biology. As suggested by recent works, a simple yet effective approach for reconstructing regulatory networks comprises the following two steps. First, the observed effects induc...

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Detalles Bibliográficos
Autores principales: Pinna, Andrea, Heise, Sandra, Flassig, Robert J, Fuente, Alberto de la, Klamt, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231426/
https://www.ncbi.nlm.nih.gov/pubmed/23924435
http://dx.doi.org/10.1186/1752-0509-7-73

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231426/
https://www.ncbi.nlm.nih.gov/pubmed/23924435
http://dx.doi.org/10.1186/1752-0509-7-73

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