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Reconstruction of large-scale regulatory networks based on perturbation graphs and transitive reduction: improved methods and their evaluation
BACKGROUND: The data-driven inference of intracellular networks is one of the key challenges of computational and systems biology. As suggested by recent works, a simple yet effective approach for reconstructing regulatory networks comprises the following two steps. First, the observed effects induc...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231426/ https://www.ncbi.nlm.nih.gov/pubmed/23924435 http://dx.doi.org/10.1186/1752-0509-7-73 |