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Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes

BACKGROUND: Type 2 diabetes, obesity and insulin resistance are characterized by hypertriglyceridemia and ectopic accumulation of lipids in liver and skeletal muscle. AGPAT6 encodes a novel glycerol-3 phosphate acyltransferase, GPAT4, which catalyzes the first step in the de novo triglyceride synthe...

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Detalles Bibliográficos
Autores principales: Snogdal, Lena Sønder, Grarup, Niels, Banasik, Karina, Wod, Mette, Jørgensen, Torben, Witte, Daniel R, Lauritzen, Torsten, Nielsen, Aneta A, Brandslund, Ivan, Christensen, Cramer, Pedersen, Oluf, Yderstræde, Knud, Beck-Nielsen, Henning, Henriksen, Jan Erik, Hansen, Torben, Højlund, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231429/
https://www.ncbi.nlm.nih.gov/pubmed/24156295
http://dx.doi.org/10.1186/1471-2350-14-113