Plasma Membrane Cholesterol as a Regulator of Human and Rodent P2X7 Receptor Activation and Sensitization

P2X7 receptors are nonselective cation channels gated by high extracellular ATP, but with sustained activation, receptor sensitization occurs, whereby the intrinsic pore dilates, making the cell permeable to large organic cations, which eventually leads to cell death. P2X7 receptors associate with c...

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Detalles Bibliográficos
Autores principales: Robinson, Lucy E., Shridar, Mitesh, Smith, Philip, Murrell-Lagnado, Ruth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Membrane Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231676/
https://www.ncbi.nlm.nih.gov/pubmed/25281740
http://dx.doi.org/10.1074/jbc.M114.574699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231676/
https://www.ncbi.nlm.nih.gov/pubmed/25281740
http://dx.doi.org/10.1074/jbc.M114.574699

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