Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector

Engineered DNA-binding proteins that manipulate the human genome and transcriptome have enabled rapid advances in biomedical research. In particular, the RNA-guided CRISPR/Cas9 system has recently been engineered to create site-specific double-strand breaks for genome editing or to direct targeted t...

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Detalles Bibliográficos
Autores principales: Kabadi, Ami M., Ousterout, David G., Hilton, Isaac B., Gersbach, Charles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231726/
https://www.ncbi.nlm.nih.gov/pubmed/25122746
http://dx.doi.org/10.1093/nar/gku749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231726/
https://www.ncbi.nlm.nih.gov/pubmed/25122746
http://dx.doi.org/10.1093/nar/gku749

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