ADAR2 induces reproducible changes in sequence and abundance of mature microRNAs in the mouse brain

Adenosine deaminases that act on RNA (ADARs) deaminate adenosines to inosines in double-stranded RNAs including miRNA precursors. A to I editing is widespread and required for normal life. By comparing deep sequencing data of brain miRNAs from wild-type and ADAR2 deficient mouse strains, we detect e...

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Detalles Bibliográficos
Autores principales: Vesely, Cornelia, Tauber, Stefanie, Sedlazeck, Fritz J., Tajaddod, Mansoureh, von Haeseler, Arndt, Jantsch, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231736/
https://www.ncbi.nlm.nih.gov/pubmed/25260591
http://dx.doi.org/10.1093/nar/gku844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231736/
https://www.ncbi.nlm.nih.gov/pubmed/25260591
http://dx.doi.org/10.1093/nar/gku844

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