ClpXP protease targets long-lived DNA translocation states of a helicase-like motor to cause restriction alleviation

We investigated how Escherichia coli ClpXP targets the helicase-nuclease (HsdR) subunit of the bacterial Type I restriction–modification enzyme EcoKI during restriction alleviation (RA). RA is a temporary reduction in endonuclease activity that occurs when Type I enzymes bind unmodified recognition...

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Detalles Bibliográficos
Autores principales: Simons, Michelle, Diffin, Fiona M., Szczelkun, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231737/
https://www.ncbi.nlm.nih.gov/pubmed/25260590
http://dx.doi.org/10.1093/nar/gku851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231737/
https://www.ncbi.nlm.nih.gov/pubmed/25260590
http://dx.doi.org/10.1093/nar/gku851

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