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ClpXP protease targets long-lived DNA translocation states of a helicase-like motor to cause restriction alleviation
We investigated how Escherichia coli ClpXP targets the helicase-nuclease (HsdR) subunit of the bacterial Type I restriction–modification enzyme EcoKI during restriction alleviation (RA). RA is a temporary reduction in endonuclease activity that occurs when Type I enzymes bind unmodified recognition...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231737/ https://www.ncbi.nlm.nih.gov/pubmed/25260590 http://dx.doi.org/10.1093/nar/gku851 |