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Protein-responsive ribozyme switches in eukaryotic cells

Genetic devices that directly detect and respond to intracellular concentrations of proteins are important synthetic biology tools, supporting the design of biological systems that target, respond to or alter specific cellular states. Here, we develop ribozyme-based devices that respond to protein l...

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Detalles Bibliográficos
Autores principales: Kennedy, Andrew B., Vowles, James V., d'Espaux, Leo, Smolke, Christina D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231745/
https://www.ncbi.nlm.nih.gov/pubmed/25274734
http://dx.doi.org/10.1093/nar/gku875