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Rio1 mediates ATP-dependent final maturation of 40S ribosomal subunits

During the last step in 40S ribosome subunit biogenesis, the PIN-domain endonuclease Nob1 cleaves the 20S pre-rRNA at site D, to form the mature 18S rRNAs. Here we report that cleavage occurs in particles that have largely been stripped of previously characterized pre-40S components, but retain the...

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Detalles Bibliográficos
Autores principales: Turowski, Tomasz W., Lebaron, Simon, Zhang, Elodie, Peil, Lauri, Dudnakova, Tatiana, Petfalski, Elisabeth, Granneman, Sander, Rappsilber, Juri, Tollervey, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231747/
https://www.ncbi.nlm.nih.gov/pubmed/25294836
http://dx.doi.org/10.1093/nar/gku878