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Quantitative effect of target translation on small RNA efficacy reveals a novel mode of interaction

Small regulatory RNAs (sRNAs) in bacteria regulate many important cellular activities under normal conditions and in response to stress. Many sRNAs bind to the mRNA targets at or near the 5′ untranslated region (UTR) resulting in translation inhibition and accelerated degradation. Often the sRNA-bin...

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Detalles Bibliográficos
Autores principales: Lavi-Itzkovitz, Anat, Peterman, Neil, Jost, Daniel, Levine, Erel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231754/
https://www.ncbi.nlm.nih.gov/pubmed/25294829
http://dx.doi.org/10.1093/nar/gku889