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Mechanical force antagonizes the inhibitory effects of RecX on RecA filament formation in Mycobacterium tuberculosis

Efficient bacterial recombinational DNA repair involves rapid cycles of RecA filament assembly and disassembly. The RecX protein plays a crucial inhibitory role in RecA filament formation and stability. As the broken ends of DNA are tethered during homologous search, RecA filaments assembled at the...

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Detalles Bibliográficos
Autores principales: Le, Shimin, Chen, Hu, Zhang, Xinghua, Chen, Jin, Patil, K. Neelakanteshwar, Muniyappa, Kalappa, Yan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231760/
https://www.ncbi.nlm.nih.gov/pubmed/25294832
http://dx.doi.org/10.1093/nar/gku899