CTCF induces histone variant incorporation, erases the H3K27me3 histone mark and opens chromatin

Insulators functionally separate active chromatin domains from inactive ones. The insulator factor, CTCF, has been found to bind to boundaries and to mediate insulator function. CTCF binding sites are depleted for the histone modification H3K27me3 and are enriched for the histone variant H3.3. In or...

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Detalles Bibliográficos
Autores principales: Weth, Oliver, Paprotka, Christine, Günther, Katharina, Schulte, Astrid, Baierl, Manuel, Leers, Joerg, Galjart, Niels, Renkawitz, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231773/
https://www.ncbi.nlm.nih.gov/pubmed/25294833
http://dx.doi.org/10.1093/nar/gku937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231773/
https://www.ncbi.nlm.nih.gov/pubmed/25294833
http://dx.doi.org/10.1093/nar/gku937

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