Trimeric HIV Env provides epitope occlusion mediated by hypervariable loops

Hypervariable loops of HIV-1 Env protein gp120 are speculated to play roles in the conformational transition of Env to the receptor binding-induced metastable state. Structural analysis of full-length Env-based immunogens, containing the entire V2 loop, displayed tighter association between gp120 su...

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Detalles Bibliográficos
Autores principales: Moscoso, Carlos G., Xing, Li, Hui, Jinwen, Hu, Jeffrey, Kalkhoran, Mohammad Baikoghli, Yenigun, Onur M., Sun, Yide, Paavolainen, Lassi, Martin, Loïc, Vahlne, Anders, Zambonelli, Carlo, Barnett, Susan W., Srivastava, Indresh K., Cheng, R. Holland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231788/
https://www.ncbi.nlm.nih.gov/pubmed/25395053
http://dx.doi.org/10.1038/srep07025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231788/
https://www.ncbi.nlm.nih.gov/pubmed/25395053
http://dx.doi.org/10.1038/srep07025

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