Perinatal systemic gene delivery using adeno-associated viral vectors

Neurodegenerative monogenic diseases often affect tissues and organs beyond the nervous system. An effective treatment would require a systemic approach. The intravenous administration of novel therapies is ideal but is hampered by the inability of such drugs to cross the blood–brain barrier (BBB) a...

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Detalles Bibliográficos
Autores principales: Karda, Rajvinder, Buckley, Suzanne M. K., Mattar, Citra N., Ng, Joanne, Massaro, Giulia, Hughes, Michael P., Kurian, Manju A., Baruteau, Julien, Gissen, Paul, Chan, Jerry K. Y., Bacchelli, Chiara, Waddington, Simon N., Rahim, Ahad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231876/
https://www.ncbi.nlm.nih.gov/pubmed/25452713
http://dx.doi.org/10.3389/fnmol.2014.00089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231876/
https://www.ncbi.nlm.nih.gov/pubmed/25452713
http://dx.doi.org/10.3389/fnmol.2014.00089

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