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Glial cells, but not neurons, exhibit a controllable response to a localized inflammatory microenvironment in vitro

The ability to design long-lasting intracortical implants hinges on understanding the factors leading to the loss of neuronal density and the formation of the glial scar. In this study, we modify a common in vitro mixed cortical culture model using lipopolysaccharide (LPS) to examine the responses o...

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Detalles Bibliográficos
Autores principales: Sommakia, Salah, Rickus, Jenna L., Otto, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231942/
https://www.ncbi.nlm.nih.gov/pubmed/25452724
http://dx.doi.org/10.3389/fneng.2014.00041