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Can pharmacogenetics explain efficacy and safety of cisplatin pharmacotherapy?

Several recent pharmacogenetic studies have investigated the variability in both outcome and toxicity in cisplatin-based therapies. These studies have focused on the genetic variability of therapeutic targets that could affect cisplatin response and toxicity in diverse type of cancer including lung,...

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Detalles Bibliográficos
Autores principales: Roco, Ángela, Cayún, Juan, Contreras, Stephania, Stojanova, Jana, Quiñones, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231946/
https://www.ncbi.nlm.nih.gov/pubmed/25452763
http://dx.doi.org/10.3389/fgene.2014.00391