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Allosteric control of the exportin CRM1 unraveled by crystal structure analysis

Nucleocytoplasmic trafficking in eukaryotic cells is a highly regulated and coordinated process which involves an increasing variety of soluble nuclear transport receptors. Generally, transport receptors specifically bind their cargo and facilitate its transition through nuclear pore complexes, aque...

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Detalles Bibliográficos
Autores principales: Monecke, Thomas, Dickmanns, Achim, Ficner, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231977/
https://www.ncbi.nlm.nih.gov/pubmed/24823279
http://dx.doi.org/10.1111/febs.12842