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Establishment and operation of a Good Manufacturing Practice-compliant allogeneic Epstein-Barr virus (EBV)-specific cytotoxic cell bank for the treatment of EBV-associated lymphoproliferative disease

Epstein-Barr virus (EBV) is associated with several malignancies, including post-transplant lymphoproliferative disorder (PTLD). Conventional treatments for PTLD are often successful, but risk organ rejection and cause significant side effects. EBV-specific cytotoxic T lymphocytes (CTLs) generated i...

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Detalles Bibliográficos
Autores principales: Vickers, Mark A, Wilkie, Gwen M, Robinson, Nicolas, Rivera, Nadja, Haque, Tanzina, Crawford, Dorothy H, Barry, Jacqueline, Fraser, Neil, Turner, David M, Robertson, Victoria, Dyer, Phil, Flanagan, Peter, Newlands, Helen R, Campbell, John, Turner, Marc L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232001/
https://www.ncbi.nlm.nih.gov/pubmed/25066775
http://dx.doi.org/10.1111/bjh.13051