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Establishment and operation of a Good Manufacturing Practice-compliant allogeneic Epstein-Barr virus (EBV)-specific cytotoxic cell bank for the treatment of EBV-associated lymphoproliferative disease
Epstein-Barr virus (EBV) is associated with several malignancies, including post-transplant lymphoproliferative disorder (PTLD). Conventional treatments for PTLD are often successful, but risk organ rejection and cause significant side effects. EBV-specific cytotoxic T lymphocytes (CTLs) generated i...
Autores principales: | Vickers, Mark A, Wilkie, Gwen M, Robinson, Nicolas, Rivera, Nadja, Haque, Tanzina, Crawford, Dorothy H, Barry, Jacqueline, Fraser, Neil, Turner, David M, Robertson, Victoria, Dyer, Phil, Flanagan, Peter, Newlands, Helen R, Campbell, John, Turner, Marc L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232001/ https://www.ncbi.nlm.nih.gov/pubmed/25066775 http://dx.doi.org/10.1111/bjh.13051 |
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