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IL-21 Modulates Activation of NKT Cells in Patients with Stage IV Malignant Melanoma
Interleukin-21 (IL-21) is a common γ-chain cytokine produced by T helper and natural killer T (NKT) cells. It has been shown to regulate the response of various lymphocyte subsets including NK, NKT, T and B cells. Owing to its potent anti-tumor function in preclinical studies and its ability to indu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232058/ https://www.ncbi.nlm.nih.gov/pubmed/25505948 http://dx.doi.org/10.1038/cti.2013.7 |