Cargando…
IL-21 Modulates Activation of NKT Cells in Patients with Stage IV Malignant Melanoma
Interleukin-21 (IL-21) is a common γ-chain cytokine produced by T helper and natural killer T (NKT) cells. It has been shown to regulate the response of various lymphocyte subsets including NK, NKT, T and B cells. Owing to its potent anti-tumor function in preclinical studies and its ability to indu...
Autores principales: | Coquet, Jonathan M, Skak, Kresten, Davis, Ian D, Smyth, Mark J, Godfrey, Dale I |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232058/ https://www.ncbi.nlm.nih.gov/pubmed/25505948 http://dx.doi.org/10.1038/cti.2013.7 |
Ejemplares similares
-
Differential antitumor immunity mediated by NKT cell subsets in vivo
por: Crowe, Nadine Y., et al.
Publicado: (2005) -
IL-21 induces in vivo immune activation of NK cells and CD8(+) T cells in patients with metastatic melanoma and renal cell carcinoma
por: Frederiksen, Klaus Stensgaard, et al.
Publicado: (2008) -
New ways to turn on NKT cells
por: Godfrey, Dale Ian, et al.
Publicado: (2011) -
Electrochemotherapy Plus IL-2+IL-12 Gene Electrotransfer in Spontaneous Inoperable Stage III–IV Canine Oral Malignant Melanoma
por: Tellado, Matías, et al.
Publicado: (2023) -
Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer
por: Smyth, Mark J., et al.
Publicado: (2005)