Interferon-alpha, immune activation and immune dysfunction in treated HIV infection

Type I interferons (IFNs) exert anti-viral effects through the induction of numerous IFN-stimulated genes and an immunomodulatory effect on innate and adaptive immune responses. This is beneficial in controlling virus infections but prolonged IFN-α activity in persistent virus infections, such as HI...

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Detalles Bibliográficos
Autores principales: Cha, Lilian, Berry, Cassandra M, Nolan, David, Castley, Allison, Fernandez, Sonia, French, Martyn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232062/
https://www.ncbi.nlm.nih.gov/pubmed/25505958
http://dx.doi.org/10.1038/cti.2014.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232062/
https://www.ncbi.nlm.nih.gov/pubmed/25505958
http://dx.doi.org/10.1038/cti.2014.1

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