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Interferon-alpha, immune activation and immune dysfunction in treated HIV infection
Type I interferons (IFNs) exert anti-viral effects through the induction of numerous IFN-stimulated genes and an immunomodulatory effect on innate and adaptive immune responses. This is beneficial in controlling virus infections but prolonged IFN-α activity in persistent virus infections, such as HI...
Autores principales: | Cha, Lilian, Berry, Cassandra M, Nolan, David, Castley, Allison, Fernandez, Sonia, French, Martyn A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232062/ https://www.ncbi.nlm.nih.gov/pubmed/25505958 http://dx.doi.org/10.1038/cti.2014.1 |
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