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Site-specific host gene modification by zinc finger nucleases: pointing the way to drug free control of HIV-1?

Anti-retroviral therapy (ART) for human immunodeficiency virus-1 (HIV-1) infection has transformed its clinical course with spectacular reductions in morbidity and mortality, turning this once fatal diagnosis into a manageable chronic infection. However, ART has its limitations. Current ART does not...

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Detalles Bibliográficos
Autores principales: Sasson, Sarah C, Kelleher, Anthony D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232064/
https://www.ncbi.nlm.nih.gov/pubmed/25505967
http://dx.doi.org/10.1038/cti.2014.12