Increase in DNA vaccine efficacy by virosome delivery and co-expression of a cytolytic protein

The potential of DNA vaccines has not been realised due to suboptimal delivery, poor antigen expression and the lack of localised inflammation, essential for antigen presentation and an effective immune response to the immunogen. Initially, we examined the delivery of a DNA vaccine encoding a model...

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Detalles Bibliográficos
Autores principales: Gargett, Tessa, Grubor-Bauk, Branka, Miller, Darren, Garrod, Tamsin, Yu, Stanley, Wesselingh, Steve, Suhrbier, Andreas, Gowans, Eric J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232068/
https://www.ncbi.nlm.nih.gov/pubmed/25505966
http://dx.doi.org/10.1038/cti.2014.13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232068/
https://www.ncbi.nlm.nih.gov/pubmed/25505966
http://dx.doi.org/10.1038/cti.2014.13

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